CD226 antibody (FITC)

Catalog No. ABIN7673212

This anti-CD226 antibody is a Rat Monoclonal antibody detecting CD226 in FACS. Suitable for Mouse.

Quick Overview for CD226 antibody (FITC) (ABIN7673212)

Target: CD226

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD226 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: 10E5

Product Details anti-CD226 Antibody (FITC)

Purpose: FITC Anti-Mouse CD226 Antibody

Purification: 0

Purity: 0

Isotype: IgG2b, kappa

Application Details

Application Notes: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: 4 °C

Storage Comment: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for CD226

Target: CD226

Alternative Name: CD226

Background:

Synonyms: DNAM-1|PTA1(platelet and T cell activation antigen 1)|TLISA1|LFA-1 associated Molecule PTA-1

Background: CD226 (DNAM-1) is constitutively expressed on native CD8+ cells and on CD4+ T cells, macrophages and NK cells.This antibody (10E5) was reported to bind about 40 % of inactivated CD4+ cells and binds only to differentiated Th1 cells, but not to Th2 or Th0 cells.It is also reported to suppress antigen-specific T cell expansion and EAE (experimental allergic encephalitis) mediated by Th1 cells.

Molecular Weight: 0

Gene ID: 225825

UniProt: Q8K4F0

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints