ECE2 antibody (AA 601-700)

Catalog No. ABIN733958

There is 1 publication for this product available. The Rabbit Polyclonal anti-ECE2 antibody is suitable to detect ECE2 in samples from Human. It has been validated for WB, FACS, IF (cc), IF (p), IHC (p) and IHC (fro).

Quick Overview for ECE2 antibody (AA 601-700) (ABIN733958)

Target: ECE2 (Endothelin Converting Enzyme 2 (ECE2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ECE2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ECE2 Antibody

Binding Specificity: AA 601-700

Purpose: ECE2 Polyclonal Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ECE2

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-ECE2 antibody (ABIN733958)

Esposito, Sarnelli, Capoccia, Cirillo, Pesce, Lu, Calì, Cuomo, Steardo: "Autologous transplantation of intestine-isolated glia cells improves neuropathology and restores cognitive deficits in β amyloid-induced neurodegeneration." in: Scientific reports, Vol. 6, pp. 22605, (2016) (PubMed).

Target Details for ECE2

Target: ECE2 (Endothelin Converting Enzyme 2 (ECE2))

Alternative Name: ECE2

Background:

Synonyms: EEF1AKMT4-ECE2 readthrough transcript protein, Methyltransferase-like region, Endothelin-converting enzyme 2 region, EEF1AKMT4-ECE2, EFCE2_HUMAN

Background: Converts big endothelin-1 to endothelin-1. May also have methyltransferase activity (By similarity). May play a role in amyloid-beta processing (By similarity).

Gene ID: 110599583, 9718

UniProt: P0DPD8

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling