Ubinuclein 1 antibody

Catalog No. ABIN7674583

This anti-Ubinuclein 1 antibody is a Rabbit Polyclonal antibody detecting Ubinuclein 1 in ELISA, WB and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for Ubinuclein 1 antibody (ABIN7674583)

Target: Ubinuclein 1 (UBN1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ubinuclein 1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Ubinuclein 1 Antibody

Purpose: UBN1-Specific antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ubinuclein 1

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for Ubinuclein 1

Target: Ubinuclein 1 (UBN1)

Alternative Name: UBN1

Background:

Synonyms: Ubinuclein-1|HIRA-binding protein|Protein VT4|Ubiquitously expressed nuclear protein|UBN1

Background: UBN1, also named as Protein VT4, belongs to the ubinuclein family. UBN1 acts as a novel regulator of senescence. It is involved in the formation of senescence-associated heterochromatin foci(SAHF), which represses expression of proliferation-promoting genes. UBN1 binds to proliferation-promoting genes. It may be required for replication-independent chromatin assembly. The antibody is specific to UBN1.

Molecular Weight: 121 kDa

UniProt: Q9NPG3