CD47 antibody (FineTest®Violet 450)
Quick Overview for CD47 antibody (FineTest®Violet 450) (ABIN7675435)
Target
See all CD47 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- FineTest®Violet 450 Anti-Human/Mouse/Rat CD47 Antibody
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Isotype
- IgG1, kappa
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Application Notes
- Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
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Comment
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FineTest®Violet Dyes are designed to be excited by the violet laser at 405 nm
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0. 1 % sodium azide, 1 %BSA, pH 7.3,
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze / thaw cycles.
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Storage
- 4 °C
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Storage Comment
- 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Expiry Date
- 12 months
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- CD47
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Alternative Name
- CD47
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Background
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Synonyms: Cd47|IAP|Integrin-associated protein|Leukocyte surface antigen CD47
Background: CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.
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Molecular Weight
- 0
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UniProt
- Q08722
Target
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