RAD52 antibody (AA 101-200)

Catalog No. ABIN735758

Product Details anti-RAD52 Antibody

Target: RAD52 (RAD52 Homolog (S. Cerevisiae) (RAD52))

Binding Specificity: AA 101-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD52 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Rad52

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for RAD52

Target: RAD52 (RAD52 Homolog (S. Cerevisiae) (RAD52))

Alternative Name: Rad52 (RAD52 Products)

Synonyms: Rad52yh antibody, RAD52 antibody, zgc:112400 antibody, LOC100223085 antibody, MGC115453 antibody, RAD52 homolog, DNA repair protein antibody, RAD52 homolog (S. cerevisiae) antibody, RAD52 homolog, DNA repair protein S homeolog antibody, recombinase antibody, DNA repair and recombination protein, putative antibody, RAD52 protein antibody, RAD52 antibody, Rad52 antibody, rad52 antibody, rad52.S antibody

Background:

Synonyms: DNA repair protein RAD52, DNA repair protein RAD52 homolog, RAD 52, RAD52 homolog S. cerevisiae, RAD52 homolog, Recombination protein RAD52, Rhabdomyosarcoma antigen MU RMS 40.23.

Background: DNA double-strand breaks can be generated by exposure to ionizing radiation or through endogenous cellular reactions. Double-strand breaks are generally thought to be repaired via one of two distinct mechanisms: homologous recombination (HR) or non-homologous end joining (NHEJ). Homologous recombination requires the activity of the members of the RAD52 epistasis group, which include RAD50, RAD51, RAD52, RAD54, RDH54/TID1, RAD55, RAD57, RAD59, MRE11, and XRS2. RAD52 can catalyze strand annealing reactions, and can form oligomers that attach to ends of single-stranded DNA.

Gene ID: 5893

Pathways: DNA Damage Repair