Recombinant CD22 antibody

Catalog No. ABIN7795327

The Mouse Monoclonal anti-CD22 antibody (Clone NCI m971) (ABIN7795327) specifically detects CD22 in ELISA, Func, IGA and Neut. The antibody is reactive with Human samples.

Quick Overview for Recombinant CD22 antibody (ABIN7795327)

Target: CD22 (CD22 Molecule (CD22))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD22 antibody is un-conjugated

Application: ELISA, Functional Studies (Func), Immunogenicity Assay (IGA), Neutralization (Neut)

Grade: In vivo Grade

Clone: NCI m971

Product Details anti-CD22 Antibody

Expression System: Mammalian cells

Purpose: In vivo Grade Recombinant Anti-human Siglec-2/CD22 Monoclonal Antibody (Clone: NCI m971), Mouse IgG2a Kappa

Characteristics: The recombinant NCI m971 antibody binds to the human CD22 protein, a sugar binding transmembrane protein, which specifically binds sialic acid with an immunoglobulin (Ig) domain located at its N-terminus. CD22 functions as an inhibitory receptor for B cell receptor (BCR) signaling. It is also involved in the B cell trafficking to Peyer's patches in mice. In mice, it has been shown that CD22 blockade restores homeostatic microglial phagocytosis in aging brains.

Purification: Protein A or G affinity column

Purity: >95 % by reducing SDS-PAGE

Endotoxin Level: < 1 EU per 1 mg of the protein by the LAL method

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: > 3 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.

Target Details for CD22

Target: CD22 (CD22 Molecule (CD22))

Alternative Name: Siglec-2/CD22