Recombinant CSF1R antibody
Quick Overview for Recombinant CSF1R antibody (ABIN7795375)
Target
See all CSF1R AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Expression System
- Mammalian cells
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Purpose
- In vivo Grade Recombinant Anti-mouse CD115 Monoclonal Antibody, Rat IgG2a Kappa (Clone: AFS98)
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Characteristics
- The rat anti-mouse CD115 (CSF1R or M-CSFR) monoclonal antibody AFS98 (rat IgG2a kappa) reacts with the mouse CD115 protein. CSF1R is found in the outer membrane of certain cell types, including microglia and macrophages. CSF1R controls the development, survival, and maintenance of microglia, and is involved in the proliferation, differentiation, and activation of macrophages. Our recombinant AFS98 antibodies have a part (variable regions) or complete amino acid sequences of the rat anti-mouse CD115 monoclonal antibody (hybridoma clone name or number: AFS98).
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Purification
- Protein A or G affinity column
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Purity
- >95 % by reducing SDS-PAGE
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Endotoxin Level
- < 1 EU per 1 mg of the protein by the LAL method
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Isotype
- IgG2a
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- > 3 mg/mL
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short time 2 to 8°C as supplied. Long time -20°C to -70°C as supplied.
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- CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))
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Alternative Name
- CD115
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Pathways
- RTK Signaling, Inositol Metabolic Process, Cell-Cell Junction Organization
Target
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