IGF1R antibody

Catalog No. ABIN7795597

The Mouse Monoclonal anti-IGF1R antibody (Clone BC10) (ABIN7795597) specifically detects IGF1R in IHC and ICC. The antibody is reactive with Human samples.

Quick Overview for IGF1R antibody (ABIN7795597)

Target: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IGF1R antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: BC10

Product Details anti-IGF1R Antibody

Purpose: Mouse anti-IGF1R Monoclonal Antibody [BC10] - BSA-Free

Purification: Purified

Immunogen: IGF1R

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Phosphate Buffered Saline (PBS) containing 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for IGF1R

Target: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Alternative Name: IGF1R

Background: IGF1R is a receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1) and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. IGF1R is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [taken from NCBI Entrez Gene (Gene ID: 3480)].

Gene ID: 3480

UniProt: P08069

Pathways: RTK Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy