PML antibody

Catalog No. ABIN7799924

This Mouse Monoclonal antibody specifically detects PML in WB and IF (p). It exhibits reactivity toward Human.

Quick Overview for PML antibody (ABIN7799924)

Target: PML (Promyelocytic Leukemia (PML))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PML antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Grade: KD Validated

Clone: 25GB8165

Product Details anti-PML Antibody

Purpose: KD-Validated PML Mouse mAb

Purification: Affinity Purified

Immunogen: Recombinant protein of human PML

Isotype: IgG1

Application Details

Application Notes: Western Blotting (WB): 1:400-1:2,000, Immunohistochemistry-Paraffin (IHC-P): 1:100-1:200

Comment:

We assess the antibodies’ specificity and selectivity using knockdown techniques. Our validation approach is straightforward: if an antibody identifies a signal in wild-type (WT) cells, but this signal is absent or noticeably reduced in gene-silenced (KD) cells, we consider the antibody to be highly specific.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS (pH 7.4) containing 50% glycerol and 0.02% sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C for one year.

Expiry Date: 12 months

Target Details for PML

Target: PML (Promyelocytic Leukemia (PML))

Alternative Name: PML

Molecular Weight: 98 kDa

Gene ID: 5371

UniProt: P29590

Pathways: p53 Signaling, Retinoic Acid Receptor Signaling Pathway, Maintenance of Protein Location, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus