DICER1 antibody (AA 1638-1899) (FL550)

Catalog No. ABIN7823245

This Mouse Monoclonal antibody specifically detects DICER1 in IHC and ICC. It exhibits reactivity toward Mouse.

Quick Overview for DICER1 antibody (AA 1638-1899) (FL550) (ABIN7823245)

Target: DICER1 (Dicer 1, Ribonuclease Type III (DICER1))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This DICER1 antibody is conjugated to FL550

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Grade: KO Validated

Clone: N167-7

Product Details anti-DICER1 Antibody (FL550)

Binding Specificity: AA 1638-1899

Purpose: Anti-Dicer Antibody FL550 Conjugate

Specificity: No off-targets reported

Cross-Reactivity: Human, Rat

Characteristics: Our Anti-Dicer mouse monoclonal primary antibody is produced in-house from hybridoma clone N167/7. It is KO validated, detects human, mouse, and rat Dicer, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Purity: Purified mAbs are >90 % specific antibody.

Immunogen: Fusion protein amino acids 1638-1899 of mouse Endoribonuclease Dicer (accession number Q8R418) produced recombinantly in E. Coli

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: For maximum recovery of product, centrifuge the vial prior to removing the cap.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C.

Expiry Date: 12 months

Target Details for DICER1

Target: DICER1 (Dicer 1, Ribonuclease Type III (DICER1))

Alternative Name: Dicer

Background:

Synonyms: Endoribonuclease Dicer (EC 3.1.26.3) (Double-strand-specific ribonuclease mDCR-1)

Description Logic: Our Anti-Dicer mouse monoclonal primary antibody is produced from hybridoma clone N167/7. It is KO validated, detects human, mouse, and rat Dicer, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Gene Name Alternatives: Dicer1 Dicer Mdcr

Molecular Weight: 215 kDa

UniProt: Q8R418

Pathways: Regulatory RNA Pathways, Stem Cell Maintenance, Ribonucleoprotein Complex Subunit Organization