RECQL2 antibody (AA 38-236) (FL594)

Catalog No. ABIN7824066

This anti-RECQL2 antibody is a Mouse Monoclonal antibody detecting RECQL2 in IHC and ICC. Suitable for Human.

Quick Overview for RECQL2 antibody (AA 38-236) (FL594) (ABIN7824066)

Target: RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RECQL2 antibody is conjugated to FL594

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: N428-12

Product Details anti-RECQL2 Antibody (FL594)

Binding Specificity: AA 38-236

Purpose: Anti-WRN Antibody FL594 Conjugate

Specificity: No off-targets reported

Cross-Reactivity: Rat

Characteristics: Our Anti-WRN mouse monoclonal primary antibody is produced in-house from hybridoma clone N428/12. It detects human and rat WRN, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Purity: Purified mAbs are >90 % specific antibody.

Immunogen: Fusion protein amino acids 38-236 (exonuclease domain) of human WRN (accession number Q14191) produced recombinantly in E. Coli

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: For maximum recovery of product, centrifuge the vial prior to removing the cap.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C.

Expiry Date: 12 months

Target Details for RECQL2

Target: RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

Alternative Name: WRN

Background:

Synonyms: Werner syndrome ATP-dependent helicase (EC 3.6.4.12) (DNA helicase, RecQ-like type 3) (RecQ3) (Exonuclease WRN) (EC 3.1.-.-) (RecQ protein-like 2)

Description Logic: Our Anti-WRN mouse monoclonal primary antibody is produced from hybridoma clone N428/12. It detects human and rat WRN, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Gene Name Alternatives: WRN RECQ3 RECQL2

Molecular Weight: 160 kDa

UniProt: Q14191

Pathways: DNA Damage Repair