RECQL2 antibody (AA 38-236)

Catalog No. ABIN7824593

The Mouse Monoclonal anti-RECQL2 antibody has been validated for WB, ELISA, IHC and ICC. It is suitable to detect RECQL2 in samples from Human.

Quick Overview for RECQL2 antibody (AA 38-236) (ABIN7824593)

Target: RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RECQL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: N428-12

Product Details anti-RECQL2 Antibody

Binding Specificity: AA 38-236

Purpose: Anti-WRN Antibody

Specificity: No off-targets reported

Cross-Reactivity: Rat

Characteristics: Our Anti-WRN mouse monoclonal primary antibody is produced in-house from hybridoma clone N428/12. It detects human and rat WRN, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Purity: Purified mAbs are >90 % specific antibody.

Immunogen: Fusion protein amino acids 38-236 (exonuclease domain) of human WRN (accession number Q14191) produced recombinantly in E. Coli

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: For maximum recovery of product, centrifuge the vial prior to removing the cap.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C.

Expiry Date: 24 months

Target Details for RECQL2

Target: RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

Alternative Name: WRN

Background:

Synonyms: Werner syndrome ATP-dependent helicase (EC 3.6.4.12) (DNA helicase, RecQ-like type 3) (RecQ3) (Exonuclease WRN) (EC 3.1.-.-) (RecQ protein-like 2)

Description Logic: Our Anti-WRN mouse monoclonal primary antibody is produced from hybridoma clone N428/12. It detects human and rat WRN, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.

Gene Name Alternatives: WRN RECQ3 RECQL2

Molecular Weight: 160 kDa

UniProt: Q14191

Pathways: DNA Damage Repair