SREBF chaperone antibody (AA 1224-1279)

Catalog No. ABIN7825872

This Rabbit Polyclonal antibody specifically detects SREBF chaperone in WB, ELISA and FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SREBF chaperone antibody (AA 1224-1279) (ABIN7825872)

Target: SREBF chaperone (SCAP)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SREBF chaperone antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-SREBF chaperone Antibody

Binding Specificity: AA 1224-1279

Purpose: Anti-SCAP Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-SCAP Antibody (ABIN7825872). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SCAP recombinant protein (Position: F1224-D1279). Human SCAP shares 100% amino acid (aa) sequence identity with both mouse and rat SCAP.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Target Details for SREBF chaperone

Target: SREBF chaperone (SCAP)

Alternative Name: SCAP

Background: This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis. Alternative splicing results in multiple transcript variants.

Molecular Weight: 140 kDa

Gene ID: 22937

UniProt: Q12770

Pathways: SARS-CoV-2 Protein Interactome