Recombinant TP53BP1 antibody (C-Term)

Catalog No. ABIN7826152

This Rabbit Monoclonal antibody specifically detects TP53BP1 in IHC. It exhibits reactivity toward Human.

Quick Overview for Recombinant TP53BP1 antibody (C-Term) (ABIN7826152)

Target: TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This TP53BP1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: HMV324

Product Details anti-TP53BP1 Antibody

Binding Specificity: C-Term

Purpose: 53BP1 antibody (HMV324)

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human 53BP1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: IHC 1:100-1:200

Comment:

Positive Control: Testis: 53BP1 staining should be strong in spermatogonia but decrease with maturation of germ cells.

Product Description/Background: 53BP1 antibody validated for immunohistochemistry on 76 different Normal Tissues

Negative Control: Testis: 53BP1 staining should be absent in mature spermatocytes and spermatids.

Protocol: Freshly cut sections should be used (less than 10 days between cutting and staining). Heat-induced antigen retrieval for 5 minutes in an autoclave at 121 °C in pH 7,8 Target Retrieval Solution buffer. Apply the antibody at a dilution of 1:100 at 37 °C for 60 minutes.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8 C. Antibody without azide - store at -20 to -80 C. Antibody is stable for 24 months. Non- hazardous. No MSD required.

Expiry Date: 24 months

Target Details for TP53BP1

Target: TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

Alternative Name: 53BP1

Background: Gene Alias: tumor protein p53 binding protein 1 , 53BP1 , TDRD30 , p202 , p53BP1

UniProt: Q12888

Pathways: DNA Damage Repair