Recombinant DPP4 antibody

Catalog No. ABIN7828156

This Rabbit Monoclonal antibody specifically detects DPP4 in WB and IHC. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Recombinant DPP4 antibody (ABIN7828156)

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Antibody Type: Recombinant Antibody

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This DPP4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A680

Product Details anti-DPP4 Antibody

Purpose: Recombinant DPP4/CD26 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human DPP4/CD26 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:1000,IHC 1:200-1:500

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for DPP4

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Alternative Name: DPP4/CD26

Background: DPP,dipeptidylpeptidase,dipeptidyl-peptidase,dipeptidyl peptidase,T-cell activation antigen CD,adenosine deaminase complexing protein,DPP4,ADABP,ADCP2,CD26,DPPIV,TP103,Dipeptidyl peptidase IV,ADCP-2,dipeptidyl-peptidase 4,dipeptidyl peptidase 4,DPP IV,dipeptidylpeptidase 4,T-cell activation antigen CD26,adenosine deaminase complexing protein 2,dipeptidylpeptidase IV,Dipeptidyl peptidase IV (DPP IV),ADABP Protein,ADCP2 Protein,CD26 Protein,DPPIV Protein,Human,TP103 Protein,DPP4/CD26 is a type II transmembrane glycoprotein expressed ubiquitously in most tissues and different cell types. The protein has a short cytoplasmic domain, transmembrane domain, a flexible stalk fragment and extracellular fragment. Both the catalytic peptide hydrolase domain and the beta-propeller ligand binding domain are located in the extracellular fragment. DPP4/CD26 is a multifunctional protein that exists in both a membrane bound form as well as an extracellular soluble form. As a peptidase, it removes N-terminal dipeptides sequentially from proteins with a proline or alanine as the penultimate P1 amino acid. DPP4/CD26 has been shown to cleave a wide range of substrates including GLP-1, BNP, etc. In addition to its peptidase activity, DPP4/CD26 interacts with multiple important cell surface ligands, such as adenosine deaminase, fibronectin, and IGF2 receptor to influence processes like T cell activation, cell migration and proliferation. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 110 kDa

Observed MW: 110 kDa

UniProt: P27487

Pathways: Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity