Recombinant FBXW7 antibody

Catalog No. ABIN7828193

The Rabbit Monoclonal anti-FBXW7 antibody is suitable to detect FBXW7 in samples from Human. It has been validated for IHC and IF.

Quick Overview for Recombinant FBXW7 antibody (ABIN7828193)

Target: FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FBXW7 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: A220

Product Details anti-FBXW7 Antibody

Purpose: Recombinant FBXW7 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human FBXW7 fragment

Isotype: IgG, kappa

Application Details

Application Notes: IHC 1:100-1:1000,IF 1:50

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for FBXW7

Target: FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))

Alternative Name: FBXW7

Background: FBX,CDC,FBXO,hCdc,FBW,SEL,FBXW7,AGO,CDC4,FBW6,FBW7,FBX30,FBXO30,FBXW6,SEL-10,SEL10,hAgo,hCdc4,Archipelago,Archipelago homolog,DKFZp686F23254,Drosophila,Drosophila),E3 ubiquitin protein ligase,F box and WD 40 domain protein 7,F box and WD 40 domain protein 7 (archipelago homolog,F box and WD repeat domain containing 7,F box protein FBW7,F box protein FBX30,F box protein SEL 10,F box protein SEL10,F-box and WD repeat domain containing 7,F-box and WD-40 domain-containing protein 7,F-box protein FBX30,F-box/WD repeat-containing protein 7,FLJ16457,homolog of,Homolog of C elegans sel 10,Homolog of C.elegans sel10,S.cerevisiae,SEL 10,Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds phosphorylated sites/phosphodegrons within target proteins and thereafter bring them to the SCF complex for ubiquitination. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: Q969H0

Pathways: Notch Signaling, EGFR Signaling Pathway