Recombinant Integrin Alpha2b antibody

Catalog No. ABIN7828315

This Rabbit Monoclonal antibody specifically detects Integrin Alpha2b in WB. It exhibits reactivity toward Human.

Quick Overview for Recombinant Integrin Alpha2b antibody (ABIN7828315)

Target: Integrin Alpha2b (CD41)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Integrin Alpha2b antibody is un-conjugated

Application: Western Blotting (WB)

Clone: A173

Product Details anti-Integrin Alpha2b Antibody

Purpose: Recombinant CD41 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human CD41 fragment

Isotype: IgG, kappa

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: CD41

Background: HPA;PPP1R;ITGA2B;BDPLT16;BDPLT2;CD41;CD41B;GP2B;GPIIb;GT;GTA;HPA3;PPP1R93;GPalpha Iib;Integrin alpha-Iib;Platelet membrane glycoprotein Iib;ITGAB;&alpha-IIb integrin-n;BDPLT16;alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex;alpha subunit;antigen CD41;antigen CD41);form 2;Integrin;Integrin alpha 2b;Integrin alpha IIb;Integrin alpha-IIb light chain;integrin αIIbβ3;ITA2B;platelet fibrinogen receptor;platelet glycoprotein IIb of IIb/IIIa complex;platelet specific antigen BAK,Integrin α-IIb/β-3 (ITGA2B) is a cell surface adhesion molecule that is the receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. In activated platelets, ITGA2B can be cleaved by proteolytic enzymes to generate disulfide bond-connected heavy and light chains, and form fibrinogen receptors together with glycoprotein IIIb, causing platelet interactions and rapid platelet aggregation, thereby Block the surface of ruptured endothelial cells. The corresponding ITGA2B gene mutation can cause platelet weakness. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Molecular Weight:

Calculated MW: 113 kDa

Observed MW: 128 kDa The actual band is not consistent with the expectation.

UniProt: P08514

Pathways: Integrin Complex