Recombinant ERBB3 antibody

Catalog No. ABIN7828520

The Rabbit Monoclonal anti-ERBB3 antibody is suitable to detect ERBB3 in samples from Human. It has been validated for IHC.

Quick Overview for Recombinant ERBB3 antibody (ABIN7828520)

Target: ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ERBB3 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: A215

Product Details anti-ERBB3 Antibody

Purpose: Recombinant c-erbB-3/HER-3 Monoclonal Antibody

Purification: Protein A purified

Immunogen: Recombinant human c-erbB-3/HER-3 fragment

Isotype: IgG, kappa

Application Details

Application Notes: IHC 1:100-1:1000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Expiry Date: 12 months

Target Details for ERBB3

Target: ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

Alternative Name: c-erbB-3/HER-3

Background: HER,LCCS,Proto-oncogene-like protein c-ErbB,Tyrosine kinase-type cell surface receptor HER,MDA-BF,p180-ErbB,p45-sErbB,p85-sErbB,ERBB3,ErbB-3,HER3,LCCS2,MDA-BF-1,c-erbB-3,c-erbB3,erbB3-S,p180-ErbB3,p45-sErbB3,p85-sErbB3,Proto-oncogene-like protein c-ErbB-3,Tyrosine kinase-type cell surface receptor HER3,EEBB3,Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it, ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase. May also be activated by CSPG5). Involved in the regulation of myeloid cell differentiation. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: P21860

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway