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CD11b antibody (Activation Site) (Biotin)

Name: CD11b antibody (Activation Site) (Biotin)
Brand: antibodies-online
SKU: ABIN7830273
Availability: InStock

The Biotin-conjugated Mouse Monoclonal anti-CD11b antibody (Clone CBRM1-5) (ABIN7830273) specifically detects CD11b in FACS and IP. The antibody is reactive with Human samples.

Catalog No. ABIN7830273

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$427.73

~~$503.21~~

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100 μg

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Quick Overview for CD11b antibody (Activation Site) (Biotin) (ABIN7830273)

Target

See all CD11b (ITGAM) Antibodies

CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reactivity

Human

Host

Mouse

Clonality

Monoclonal

Conjugate

This CD11b antibody is conjugated to Biotin

Application

Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone

CBRM1-5

Discover our top product ITGAM Primary Antibody

Binding Specificity
34

16

14

8

6

5

5

5

5

4

4

3

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Activation Site

Purpose

Anti-Hu CD11b (activation epitope) Biotin

Characteristics

The mouse monoclonal antibody CBRM1/5 recognizes an activation-dependent epitope on extracellular part of CD11b (Mac-1alpha), a 165-170 kDa type 1 transmembrane protein mainly expressed on monocytes, granulocytes and NK-cells. The antibody recognizes a subset of CD11b molecules on neutrophils and monocytes activated with chemoattractants or phorbol esters and it does not recognize CD11b on non-activated cells.

Purification

Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.

Isotype

IgG1, kappa
anti-Integrin alpha M (ITGAM) (AA 145-340) antibody
ITGAM Reactivity: Human IHC, WB, IF Host: Rabbit Polyclonal unconjugated

anti-Integrin alpha M (ITGAM) (AA 520-570) antibody
ITGAM Reactivity: Human, Mouse, Rat FACS Host: Rabbit Polyclonal unconjugated

anti-Integrin alpha M (ITGAM) (AA 253-282), (N-Term) antibody
ITGAM Reactivity: Human FACS, WB, IHC (p) Host: Rabbit Polyclonal RB17991 unconjugated

anti-Integrin alpha M (ITGAM) (AA 77-180) antibody
ITGAM Reactivity: Human, Mouse, Rat FACS, WB, IHC (fro), ELISA, IHC (p), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated

anti-Integrin alpha M (ITGAM) (AA 31-160) antibody
ITGAM Reactivity: Rat IHC, WB, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Integrin alpha M (ITGAM) antibody (Biotin)
ITGAM Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-174 Biotin

anti-Integrin alpha M (ITGAM) antibody (FITC)
ITGAM Reactivity: Human FACS Host: Mouse Monoclonal MEM-174 FITC

anti-Integrin alpha M (ITGAM) antibody (PE)
ITGAM Reactivity: Human FACS Host: Mouse Monoclonal MEM-174 PE

anti-Integrin alpha M (ITGAM) (AA 623-728) antibody
ITGAM Reactivity: Human ICC, ELISA Host: Mouse Monoclonal 3A10H5 unconjugated

anti-Integrin alpha M (ITGAM) (AA 941-1074) antibody
ITGAM Reactivity: Human IHC, WB, StM Host: Mouse Monoclonal ITGAM-3340 unconjugated

Application Notes

Flow cytometry: Recommended dilution: 1-5 μg/mL.

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Do not freeze

Storage

4 °C

Storage Comment

Store at 2-8°C. Do not freeze.
Target

CD11b (ITGAM) (Integrin alpha M (ITGAM))

Alternative Name

CD11b

Background

NCBI Full Gene Name: integrin subunit alpha M
Other names: Mac-1, Integrin alpha M, ITGAM, CR3A, MO1A, MAC1A
Gene name: ITGAM

Gene ID

3684

UniProt

P11215

Pathways

Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation