Recombinant TGFB1 antibody

Catalog No. ABIN7857829

The Mouse Monoclonal anti-TGFB1 antibody (Clone rTGFB17) (ABIN7857829) specifically detects TGFB1 in IHC. The antibody is reactive with Human samples.

Quick Overview for Recombinant TGFB1 antibody (ABIN7857829)

Target: TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TGFB1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: RTGFB17

Product Details anti-TGFB1 Antibody

Expression System: CHO Cells

Purpose: Recombinant Transforming Growth Factor Beta 1 (TGFB1) (Marker of Tumor Invasiveness) Antibody

Specificity: Transforming growth factor beta (TGFB) is a potent cell regulatory polypeptide homodimer of 25 kD. It variably affects cell growth, differentiation and other aspects of cellular metabolism such as extracellular matrix production. Its effect depends upon the cell type and other growth factors present but in general, TGFB inhibits the growth of epithelial cells and stimulates the growth of mesenchymal cells.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogen: Prokaryotic recombinant protein corresponding to the full length mature transforming growth factor beta1 molecule

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for TGFB1

Target: TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Alternative Name: Transforming Growth Factor Beta 1

Background:

TGFB | TGFB1 | Transforming growth factor beta-1 proprotein

Human placenta.

Molecular Weight: 13kDa

Gene ID: 7040

UniProt: P01137

Pathways: EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints