PAX4 antibody (AA 1-200)

Catalog No. ABIN7858644

The Mouse Monoclonal anti-PAX4 antibody is suitable to detect PAX4 in samples from Human. It has been validated for IHC.

Quick Overview for PAX4 antibody (AA 1-200) (ABIN7858644)

Target: PAX4 (Paired Box 4 (PAX4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PAX4 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: PAX4-7599

Product Details anti-PAX4 Antibody

Binding Specificity: AA 1-200

Purpose: PAX4 Antibody

Specificity: Pax-4 (paired box gene 4) protein influences normal differentiation of Insulinproducing ≤ cells and influences normal pancreatic islet development. Pax-4 protein is a transcriptional repressor that binds to a common cis element in the Glucagon, Insulin and Somatostatin promoters. Mouse Pax-4 transcript is present in pancreatic islets, and the islet ≤ cell lines MIN6, ≤ TC and NIT1. Differentiation of endoderm-derived endocrine pancreas is mediated through Pax-4 and Pax-6. Pax-4 may act as a Pax-6 repressor due to the competition for binding sites and lower transactivation potential of Pax-4. The human Pax-4 gene encodes a deduced 350 amino acid protein that is 80 % identical to the deduced mouse Pax-4 protein.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-200) of human PAX4 protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for PAX4

Target: PAX4 (Paired Box 4 (PAX4))

Alternative Name: PAX4

Background:

KPD, MODY9, Paired box 4

DAUDI or Ramos cells. Human tonsil|lymph node or colon carcinoma.|Raji|spleen

Molecular Weight: 38kDa

Gene ID: 5078, 129706

UniProt: O43316