HBEGF antibody (AA 1-208)

Catalog No. ABIN7858753

The Mouse Monoclonal anti-HBEGF antibody (Clone HBEGF-9503) (ABIN7858753) specifically detects HBEGF in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for HBEGF antibody (AA 1-208) (ABIN7858753)

Target: HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HBEGF antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: HBEGF-9503

Product Details anti-HBEGF Antibody

Binding Specificity: AA 1-208

Purpose: HBEGF / DTR Antibody

Specificity: Enables growth factor activity and heparin binding activity. Involved in several processes, including epidermal growth factor receptor signaling pathway, positive regulation of protein kinase B signaling, and positive regulation of wound healing. Located in cell surface and extracellular space. Implicated in glomerulosclerosis and perinatal necrotizing enterocolitis.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa1-208) of human HBEGF protein (exact sequence is proprietary)

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for HBEGF

Target: HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

Alternative Name: HBEGF

Background:

diphtheria toxin receptor (heparin-binding EGF-like growth factor), diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor), heparin-binding epidermal growth factor

RAW 264.7

Molecular Weight: 23kDa

Gene ID: 1839, 799

UniProt: Q99075

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway