Recombinant Annexin a1 antibody

Catalog No. ABIN7862929

The Mouse Monoclonal anti-Annexin a1 antibody (Clone rANXA1-4310) (ABIN7862929) specifically detects Annexin a1 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Rabbit, Guinea Pig and Hamster samples.

Quick Overview for Recombinant Annexin a1 antibody (ABIN7862929)

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat, Rabbit, Guinea Pig, Hamster

Host: Mouse

Clonality: Monoclonal

Conjugate: This Annexin a1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: RANXA1-4310

Product Details anti-Annexin a1 Antibody

Purpose: Recombinant Annexin A1 / (Hairy Cell Leukemia Marker) Antibody

Specificity: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human Annexin A1 protein

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Annexin a1

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Alternative Name: Annexin A1

Background:

ANXA1, ANX1, Annexin-1, Chromobindin-9, LPC1, p35

Human Intestine, Lung, A549 or K562 cell lysates. Human esophagus, Placenta or Prostate.

Molecular Weight: 38kDa

Gene ID: 301, 494173

UniProt: P04083

Pathways: Hormone Transport