alpha Tubulin antibody (AA 1-115)

Catalog No. ABIN7863479

This Mouse Monoclonal antibody specifically detects alpha Tubulin in IHC. It exhibits reactivity toward Human.

Quick Overview for alpha Tubulin antibody (AA 1-115) (ABIN7863479)

Target: alpha Tubulin (TUBA1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This alpha Tubulin antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: TUBA-3038

Product Details anti-alpha Tubulin Antibody

Binding Specificity: AA 1-115

Purpose: Tubulin-alpha (Microtubule Marker) Antibody

Specificity: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. This MAb recognizes an epitope of alpha-tubulin. The alpha-tubulin is globular protein that exists in cells as part of soluble alpha/beta-tubulin dimer or it is polymerized into microtubules. In different species it is coded by multiple tubulin genes that form tubulin classes (in human 6 genes). Expressed tubulin genes are named tubulin isotypes. Some of the tubulin isotypes are expressed ubiquitously, while some have more restricted tissue expression. Alpha-tubulin is also subject of numerous post-translational modifications. Tubulin isotypes and their posttranslational modifications are responsible for multiple tubulin charge variants - tubulin isoforms. Heterogeneity of alpha-tubulin is concentrated in C-terminal structural domain

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate.

Immunogen: Recombinant fragment (aa 1-115) of human Tubulin Alpha protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for alpha Tubulin

Target: alpha Tubulin (TUBA1)

Alternative Name: Tubulin-alpha

Background:

Alpha-tubulin 1, Hum a tub1, Hum a tub2, Testis-specific alpha-tubulin, TUBA1, TUBA1A, Tuba4a, Tubulin alpha-1 chain, Tubulin H2-alpha, Tubulin, alpha 1 (testis specific), Tubulin, alpha 4a

Human prostate, lung or colon tissues (IHC).

Molecular Weight: 55kDa

Gene ID: 7277, 75318

UniProt: P68363, P68366

Pathways: Microtubule Dynamics