MRPL41 antibody (AA 210-290)

Catalog No. ABIN7862460

The Rabbit Polyclonal anti-MRPL41 antibody is suitable to detect MRPL41 in samples from Human. It has been validated for WB, ELISA, IHC and IF.

Quick Overview for MRPL41 antibody (AA 210-290) (ABIN7862460)

Target: MRPL41 (Mitochondrial Ribosomal Protein L41 (MRPL41))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL41 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-MRPL41 Antibody

Binding Specificity: AA 210-290

Purpose: Rabbit Anti-PIG3 Polyclonal Antibody

Specificity: PIG3 Polyclonal Antibody detects endogenous levels of PIG3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human PIG3 at AA range: 210-290

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for MRPL41

Target: MRPL41 (Mitochondrial Ribosomal Protein L41 (MRPL41))

Alternative Name: PIG3

Background: TP53I3, PIG3, Quinone oxidoreductase PIG3, Tumor protein p53-inducible protein 3, p53-induced gene 3 proteinTumor protein p53 inducible protein 3 encoded by TP53I3 is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. TP53I3 is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate TP53I3 by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Alternatively spliced transcript variants encoding different isoforms have been found for TP53I3.

Molecular Weight: 36kD

Gene ID: 9540

UniProt: Q53FA7

Pathways: p53 Signaling