AMACR antibody

Catalog No. ABIN7865557

The Mouse Monoclonal anti-AMACR antibody (Clone IHC504) (ABIN7865557) specifically detects AMACR in IHC. The antibody is reactive with Human samples.

Quick Overview for AMACR antibody (ABIN7865557)

Target: AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AMACR antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: IHC504

Product Details anti-AMACR Antibody

Purpose: anti-p504s mouse monoclonal, IHC504, purified

Purification: affinity chromatography

Immunogen: Recombinant Human p504s

Isotype: IgG1

Application Details

Application Notes: Optional[ICC/IF_dilution]: 1:50-1:200 (microwave treatment recommended)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Tris pH 7.3-7.7 with 1 % BSA and 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: store at 2 - 8 °C

Target Details for AMACR

Target: AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

Alternative Name: p504s

Background: P504s, also known as α-Methylacyl Coenzyme A Racemase (AMACR), is an enzyme localized in the peroxisome and mitochondria that functions in β-oxidation of branched chain fatty acids, as well as bile synthesis. AMACR has been clinically indicated as a tissue biomarker for prostate cancer and colorectal cancer, as well as high-grade prostatic intraepithelial neoplasia, a precursor lesion of prostate cancer. p504s overexpression has also been detected in a number of other cancers including ovarian, breast, bladder, lung, and renal cell carcinomas, lymphoma, and melanoma.

Pathways: Monocarboxylic Acid Catabolic Process