CD36 antibody
Quick Overview for CD36 antibody (ABIN7865587)
Target
See all CD36 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- anti-CD36 mouse monoclonal, EBS-CD-023, purified
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Purification
- affinity chromatography
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Immunogen
- gp88 purified from human platelets
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Isotype
- IgG2b kappa
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Application Notes
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ICC/IF_dilution: 1:50-1:100 (1-2 μg/mL)
FACS_dilution: 1-2 μg/million cells
IHC-paraffin_dilution: 1:50-1:100 (1-2 μg/mL)
IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 100 μg/mL
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Buffer
- PBS with 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- store at 2 - 8 °C
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- CD36
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Alternative Name
- CD36
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Background
- CD36 is a 80-90 kDa protein, expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P.falciparum malaria-infected erythrocytes, and sickle erythrocytes. CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Positive control: HEL, U937 or C32 melanoma cells. Platelets, monocytes, macrophages, umbilical vein endothelium, microvascular endothelial cells in tonsil.
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Pathways
- TLR Signaling, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, Lipid Metabolism, S100 Proteins
Target
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