Integrin Alpha2b antibody

Catalog No. ABIN7865660

This Mouse Monoclonal antibody specifically detects Integrin Alpha2b in FACS, IHC, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for Integrin Alpha2b antibody (ABIN7865660)

Target: Integrin Alpha2b (CD41)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin Alpha2b antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: 96-2C1

Product Details anti-Integrin Alpha2b Antibody

Purpose: anti-CD41a mouse monoclonal, 96-2C1, purified

Purification: affinity chromatography

Immunogen: stimulated human PBL

Isotype: IgG1 kappa

Application Details

Application Notes:

ICC/IF_dilution: 1:50-1:100 (1-2 μg/mL)

FACS_dilution: 1-2 μg/million cells

IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS with 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: store at 2 - 8 °C

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: CD41a

Background: 96-2C1 reacts with a calcium-dependent complex of CD41/CD61 (GPIIb/IIIa, integrin IIa/3), a dimer of 90 and 140 kDa, present on the membrane of normal platelets and megakaryocytes. This complex forms the receptor of fibrinogen, fibronectin and Von Willebrand factor, and mediates platelet adhesion and aggregation. MAbs to CD41a have been shown to have anti-proliferative effects on various lymphoid cell lines, particularly those derived from large cell lymphomas. 96-2C1 was typed at the IIId HLDA workshop. Positive control: KG1a, HEL cells, and human platelets in lymph nodes or tonsils.

Pathways: Integrin Complex