Prosaposin antibody

Catalog No. ABIN7865723

This Mouse Monoclonal antibody specifically detects Prosaposin in IHC. It exhibits reactivity toward Human.

Quick Overview for Prosaposin antibody (ABIN7865723)

Target: Prosaposin (PSAP)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Prosaposin antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: IHC655

Product Details anti-Prosaposin Antibody

Purpose: anti-PSAP mouse monoclonal, IHC655, purified

Purification: affinity chromatography

Immunogen: Recombinant Human PSAP

Isotype: IgG1 kappa

Application Details

Application Notes: Optional[ICC/IF_dilution]: 1:50-1:200 (microwave treatment recommended)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Tris pH 7.3-7.7 with 1 % BSA and 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: store at 2 - 8 °C

Target Details for Prosaposin

Target: Prosaposin (PSAP)

Alternative Name: PSAP

Background: Prostatic Specific Acid Phosphatase (PSAP) is a prostatic enzyme found in the glandular epithelium of the prostate. PSAP levels are elevated in hyperplastic prostate and prostate carcinoma, with the highest levels being detected in metastasized prostate cancer. Moderate overexpression of PSAP is also characteristic of diseases of the bone (such as Paget's disease or hyperparathyroidism), diseases of blood cells (such as sicklecell disease), multiple myeloma, or lysosomal storage diseases (such as Gaucher's disease). PSAP is considered more sensitive, yet less specific, than PSA, however Anti-PSAP can act as a useful complement to Anti-PSA under suitable clinical contexts.

Pathways: Positive Regulation of Endopeptidase Activity