CD46 antibody (PE)

Catalog No. ABIN7867164

The Rabbit Monoclonal anti-CD46 antibody is suitable to detect CD46 in samples from Human. It has been validated for FACS.

Quick Overview for CD46 antibody (PE) (ABIN7867164)

Target: CD46

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD46 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: DM145

Product Details anti-CD46 Antibody (PE)

Purpose: PE-conjugated Anti-CD46 antibody(DM145), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C-8°C for 6 months

Expiry Date: 6 months

Target Details for CD46

Target: CD46

Alternative Name: CD46

Background:

Synonyms: CD46,AHUS2,MCP,MIC10,TLX,TRA2.10

Target Background: The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization