Recombinant CCR1 antibody (PE)

Catalog No. ABIN7867198

The PE-conjugated Rabbit Chimeric anti-CCR1 antibody (Clone DMC465) (ABIN7867198) specifically detects CCR1 in FACS. The antibody is reactive with Human samples.

Quick Overview for Recombinant CCR1 antibody (PE) (ABIN7867198)

Target: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This CCR1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: DMC465

Product Details anti-CCR1 Antibody (PE)

Purpose: PE-conjugated Anti-CCR1 antibody(DMC465), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C-8°C for 6 months

Expiry Date: 6 months

Target Details for CCR1

Target: CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))

Alternative Name: CCR1

Background:

Synonyms: CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1

Target Background: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008]

UniProt: P32246