IL15RA antibody (PE)

Catalog No. ABIN7867334

This Rabbit Monoclonal antibody specifically detects IL15RA in FACS. It exhibits reactivity toward Human.

Quick Overview for IL15RA antibody (PE) (ABIN7867334)

Target: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IL15RA antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: DM206

Product Details anti-IL15RA Antibody (PE)

Purpose: PE-conjugated Anti-IL15RA antibody(DM206), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C-8°C for 6 months

Expiry Date: 6 months

Target Details for IL15RA

Target: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Alternative Name: IL15RA

Background:

Synonyms: CD215

Target Background: This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1:BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.

UniProt: Q13261

Pathways: JAK-STAT Signaling