Recombinant IL-5 antibody (PE)

Catalog No. ABIN7867340

This Rabbit Chimeric antibody specifically detects IL-5 in FACS. It exhibits reactivity toward Human.

Quick Overview for Recombinant IL-5 antibody (PE) (ABIN7867340)

Target: IL-5 (IL5) (Interleukin 5 (IL5))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This IL-5 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: DMC274

Product Details anti-IL-5 Antibody (PE)

Purpose: PE-conjugated Anti-IL5 antibody(DMC274), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C-8°C for 6 months

Expiry Date: 6 months

Target Details for IL-5

Target: IL-5 (IL5) (Interleukin 5 (IL5))

Alternative Name: IL5

Background:

Synonyms: IL-5,TRF,Interleukin-5,EDF

Target Background: This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2:GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.

UniProt: P05113

Pathways: JAK-STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour