Neuregulin 1 antibody (PE)

Catalog No. ABIN7867383

The Rabbit Monoclonal anti-Neuregulin 1 antibody is suitable to detect Neuregulin 1 in samples from Human. It has been validated for FACS.

Quick Overview for Neuregulin 1 antibody (PE) (ABIN7867383)

Target: Neuregulin 1 (NRG1)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Neuregulin 1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: DM209

Product Details anti-Neuregulin 1 Antibody (PE)

Purpose: PE-conjugated Anti-NRG1 antibody(DM209), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C-8°C for 6 months

Expiry Date: 6 months

Target Details for Neuregulin 1

Target: Neuregulin 1 (NRG1)

Alternative Name: NRG1

Background:

Synonyms: ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, MSTP131, NDF, NRG1-IT2, SMDF

Target Background: The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).

UniProt: Q02297

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation