Poliovirus Receptor antibody (PE)

Catalog No. ABIN7867403

This Rabbit Monoclonal antibody specifically detects Poliovirus Receptor in FACS. It exhibits reactivity toward Human.

Quick Overview for Poliovirus Receptor antibody (PE) (ABIN7867403)

Target: Poliovirus Receptor (PVR)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Poliovirus Receptor antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: DM146

Product Details anti-Poliovirus Receptor Antibody (PE)

Purpose: PE-conjugated Anti-CD155 antibody(DM146), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C-8°C for 6 months

Expiry Date: 6 months

Target Details for Poliovirus Receptor

Target: Poliovirus Receptor (PVR)

Alternative Name: CD155

Background:

Synonyms: PVR, FLJ25946, PVS, CD155, TAGE4, HVED, NECL5

Target Background: The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1:DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: P15151

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome