Recombinant SELPLG antibody (PE)

Catalog No. ABIN7867426

The PE-conjugated Rabbit Chimeric anti-SELPLG antibody (Clone DMC283) (ABIN7867426) specifically detects SELPLG in FACS. The antibody is reactive with Human samples.

Quick Overview for Recombinant SELPLG antibody (PE) (ABIN7867426)

Target: SELPLG (Selectin P Ligand (SELPLG))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This SELPLG antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: DMC283

Product Details anti-SELPLG Antibody (PE)

Purpose: PE-conjugated Anti-CD162 antibody(DMC283), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C-8°C for 6 months

Expiry Date: 6 months

Target Details for SELPLG

Target: SELPLG (Selectin P Ligand (SELPLG))

Alternative Name: SELPLG

Background:

Synonyms: PSGL-1,PSGL1,CD162,SELPLG,Selectin P ligand

Target Background: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.

UniProt: Q14242