EPH Receptor B4 antibody (AA 1-200)

Catalog No. ABIN7868473

The Mouse Monoclonal anti-EPH Receptor B4 antibody (Clone EPHB4-6391) (ABIN7868473) specifically detects EPH Receptor B4 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for EPH Receptor B4 antibody (AA 1-200) (ABIN7868473)

Target: EPH Receptor B4 (EPHB4)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPH Receptor B4 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: EPHB4-6391

Product Details anti-EPH Receptor B4 Antibody

Binding Specificity: AA 1-200

Purpose: EPH Receptor B4 Antibody / EPHB4

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the EPH Receptor B4 antibody.

Isotype: IgG2, kappa

Application Details

Application Notes: Optimal dilution of the EPH Receptor B4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot the EPH Receptor B4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for EPH Receptor B4

Target: EPH Receptor B4 (EPHB4)

Alternative Name: EPH Receptor B4

Background: The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date. While the biological activities of these receptors have yet to be determined, there is increasing evidence that they are involved in central nervous system function and in development. The Eph subfamily receptors of human origin (and their murine/avian homologs) include EphA1 (Eph), EphA2 (Eck), EphA3 (Hek4), EphA4 (Hek8), EphA5 (Hek7), EphA6 (Hek12), EphA7 (Hek11/MDK1), EphA8 (Hek3), EphB1 (Hek6), EphB2 (Hek5), EphB3 (Cek10, Hek2), EphB4 (Htk), EphB5 (Hek9) and EphB6 (Mep). Ligands for Eph receptors include ephrin-A4 (LERK-4) which binds EphA3 and EphB1. In addition, ephrin-A2 (ELF-1) has been described as the ligand for EphA4, ephrin-A3 (Ehk1-L) as the ligand for EphA5 and ephrin-B2 (Htk-L) as the ligand for EphB4 (Htk).

UniProt: P54760

Pathways: RTK Signaling