BRD2 antibody (AA 1-214)

Catalog No. ABIN7868829

The Rabbit Polyclonal anti-BRD2 antibody is suitable to detect BRD2 in samples from Human. It has been validated for WB, ELISA, FACS and IF.

Quick Overview for BRD2 antibody (AA 1-214) (ABIN7868829)

Target: BRD2 (Bromodomain Containing 2 (BRD2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRD2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-BRD2 Antibody

Binding Specificity: AA 1-214

Purpose: BRD2 Antibody

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids M1-Q214) was used as the immunogen for the BRD2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the BRD2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the BRD2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for BRD2

Target: BRD2 (Bromodomain Containing 2 (BRD2))

Alternative Name: BRD2

Background: Bromodomain-containing protein 2 is a protein that in humans is encoded by the BRD2 gene. It is mapped to 6p21.32. This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene.

UniProt: P25440

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection