Calnexin antibody (AA 1-300)

Catalog No. ABIN7869119

This Mouse Monoclonal antibody specifically detects Calnexin in WB, ELISA and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Calnexin antibody (AA 1-300) (ABIN7869119)

Target: Calnexin (CANX)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Calnexin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CANX-1543

Product Details anti-Calnexin Antibody

Binding Specificity: AA 1-300

Purpose: Calnexin Antibody

Purification: Protein G affinity chromatography

Immunogen: A portion of amino acids 1-300 from the human protein was used as the immunogen for the Calnexin antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Titering of the Calnexin antibody may be required for optimal performance.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Calnexin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Calnexin

Target: Calnexin (CANX)

Alternative Name: Calnexin

Background: It recognizes a protein of 90 kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.

UniProt: P27824

Pathways: MAPK Signaling, Thyroid Hormone Synthesis