Recombinant Calnexin antibody (N-Term)

Catalog No. ABIN7869159

The Rabbit Monoclonal anti-Calnexin antibody is suitable to detect Calnexin in samples from Human. It has been validated for WB, ELISA and IHC (p).

Quick Overview for Recombinant Calnexin antibody (N-Term) (ABIN7869159)

Target: Calnexin (CANX)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Calnexin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: CANX-9147R

Product Details anti-Calnexin Antibody

Binding Specificity: AA 1-300, N-Term

Purpose: Recombinant Calnexin Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A recombinant N-terminal region fragment of human Calnexin protein (within amino acids 1-300) was used as the immunogen for the recombinant Calnexin antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the recombinant Calnexin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the recombinant Calnexin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Calnexin

Target: Calnexin (CANX)

Alternative Name: Calnexin

Background: It recognizes a protein of 90 kDa, which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.

UniProt: P27824

Pathways: MAPK Signaling, Thyroid Hormone Synthesis