MRPL41 antibody (AA 1-332)

Catalog No. ABIN7869202

The Rabbit Polyclonal anti-MRPL41 antibody (ABIN7869202) specifically detects MRPL41 in WB, ELISA and IHC (p). The antibody is reactive with Human samples.

Quick Overview for MRPL41 antibody (AA 1-332) (ABIN7869202)

Target: MRPL41 (Mitochondrial Ribosomal Protein L41 (MRPL41))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL41 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MRPL41 Antibody

Binding Specificity: AA 1-332

Purpose: PIG3 Antibody / TP53I3

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids M1-Q332) was used as the immunogen for the PIG3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PIG3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PIG3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for MRPL41

Target: MRPL41 (Mitochondrial Ribosomal Protein L41 (MRPL41))

Alternative Name: PIG3

Background: Putative quinone oxidoreductase is an enzyme that in humans is encoded by the TP53I3 gene. The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt: Q53FA7

Pathways: p53 Signaling