Recombinant UPK1A antibody (AA 100-200)

Catalog No. ABIN7869753

The Rabbit Monoclonal anti-UPK1A antibody is suitable to detect UPK1A in samples from Human. It has been validated for ELISA and IHC (p).

Quick Overview for Recombinant UPK1A antibody (AA 100-200) (ABIN7869753)

Target: UPK1A (Uroplakin 1a (UPK1A))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This UPK1A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: UPK1A-8704R

Product Details anti-UPK1A Antibody

Binding Specificity: AA 100-200

Purpose: Uroplakin 1A Antibody / UPK1A

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 100-200) from the human protein was used as the immunogen for the Uroplakin 1A antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the Uroplakin 1A antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Uroplakin 1A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for UPK1A

Target: UPK1A (Uroplakin 1a (UPK1A))

Alternative Name: Uroplakin 1A

Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression.

UniProt: O00322