Recombinant HLA-ABC antibody (AA 100-300)
Quick Overview for Recombinant HLA-ABC antibody (AA 100-300) (ABIN7869839)
Target
See all HLA-ABC AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 100-300
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Purpose
- HLA-ABC Antibody / MHC I
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Purification
- Protein A/G affinity
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Immunogen
- A recombinant partial protein sequence (within amino acids 100-300) from the human protein was used as the immunogen for the HLA-ABC antibody.
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Isotype
- IgG, kappa
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anti-HLA-ABC (HLA-ABC) antibody
HLA-ABC Reactivity: Human, Cow, Baboon, Cat, Monkey FACS, WB, IHC, IHC (fro), IP Host: Mouse Monoclonal W6-32 unconjugated
anti-HLA-ABC (HLA-ABC) antibody (PE)HLA-ABC Reactivity: Human, Cow, Baboon, Cynomolgus, Rhesus Monkey, Macaque, Shrew, Chimpanzee, Gorilla FACS Host: Mouse Monoclonal W6-32 PE
anti-HLA-ABC (HLA-ABC) antibodyHLA-ABC Reactivity: Human, Cow, Baboon, Macaque, Cat, Monkey, Primate, Chimpanzee FACS, IHC (fro), IF, IP, Func, EIA, DNA Mic Host: Mouse Monoclonal W6-32 unconjugated
anti-HLA-ABC (HLA-ABC) antibodyHLA-ABC Reactivity: Human, Cow, Cat, Monkey, Primate FACS, IHC (fro), IF, IP, EIA Host: Mouse Monoclonal W6-32 unconjugated
anti-HLA-ABC (HLA-ABC) antibody (Biotin)HLA-ABC Reactivity: Human, Cow, Baboon, Cynomolgus, Rhesus Monkey, Macaque, Shrew FACS Host: Mouse Monoclonal W6-32 Biotin
anti-HLA-ABC (HLA-ABC) antibody (FITC)HLA-ABC Reactivity: Human, Cow, Baboon, Cynomolgus, Rhesus Monkey, Macaque, Shrew FACS Host: Mouse Monoclonal W6-32 FITC
anti-HLA-ABC (HLA-ABC) antibodyHLA-ABC Reactivity: Human FACS, IHC, IHC (fro), IP Host: Rat Monoclonal YTH862-2 unconjugated
anti-HLA-ABC (HLA-ABC) antibodyHLA-ABC Reactivity: Human, Mouse, Non-Human Primate FACS, IF Host: Mouse Monoclonal 246-B8-E7 unconjugated
anti-HLA-ABC (HLA-ABC) antibody (PE)GMP Grade HLA-ABC Reactivity: Human, Baboon, Cynomolgus, Rhesus Monkey FACS Host: Mouse Monoclonal W6-32 PE
anti-HLA-ABC (HLA-ABC) antibody (FITC)GMP Grade HLA-ABC Reactivity: Human, Baboon, Cynomolgus, Rhesus Monkey FACS Host: Mouse Monoclonal W6-32 FITC
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Application Notes
- Optimal dilution of the HLA-ABC antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the HLA-ABC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- HLA-ABC
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Alternative Name
- HLA-ABC
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Background
- Major Histocompatibility Complex (MHC) is a genetic region on chromosomes composed of tightly linked highly polymorphic gene loci that encode cell surface specific proteins, depending on the structure and function of genes and coding products. We divide MHC into class I (telomeric), class II (centromeric) and class III gene regions. Endogenous antigen presentation is presented by the major histocompatibility complex I (MHC I ) pathway. Intracytoplasmic proteins are decomposed into peptides during protease degradation, which in turn are delivered by HSP41 and HSP90 proteins to TAP on the membrane. MHC I is widely distributed on the surface of almost all nucleated cells, including spleen, lymph nodes and thymus lymphocytes in normal tissues. It is also expressed in skin, lung, kidney, liver and heart tissues. It is also widely expressed in tumor tissues. MHC molecular typing is related to the matching of organ transplantation and bone marrow transplantation, as well as a variety of autoimmune diseases.
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UniProt
- P01889
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Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Target
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