Recombinant Uroplakin 1B antibody (AA 109-229)

Catalog No. ABIN7870053

The Rabbit Monoclonal anti-Uroplakin 1B antibody is suitable to detect Uroplakin 1B in samples from Human. It has been validated for IHC (p).

Quick Overview for Recombinant Uroplakin 1B antibody (AA 109-229) (ABIN7870053)

Target: Uroplakin 1B (UPK1B)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Uroplakin 1B antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: UPK1B-8976R

Product Details anti-Uroplakin 1B Antibody

Binding Specificity: AA 109-229

Purpose: UPK1B Antibody / Uroplakin 1B

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 109-229) from the human protein was used as the immunogen for the UPK1B antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the UPK1B antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the UPK1B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Uroplakin 1B

Target: Uroplakin 1B (UPK1B)

Alternative Name: UPK1B

Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. UPK1B is expressed by terminally differentiated urothelial cells.

UniProt: O75841