UPK1A antibody (AA 114-173)

Catalog No. ABIN7870163

This Mouse Monoclonal antibody specifically detects UPK1A in ELISA and IHC (p). It exhibits reactivity toward Human.

Quick Overview for UPK1A antibody (AA 114-173) (ABIN7870163)

Target: UPK1A (Uroplakin 1a (UPK1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This UPK1A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: UPK1A-2922

Product Details anti-UPK1A Antibody

Binding Specificity: AA 114-173

Purpose: UPK1A Antibody / Uroplakin 1A (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: Amino acids 114-173 were used as the immunogen for the UPK1A antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the UPK1A antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the UPK1A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for UPK1A

Target: UPK1A (Uroplakin 1a (UPK1A))

Alternative Name: UPK1A

Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression.

UniProt: O00322