UPK1A antibody (AA 114-173)

Catalog No. ABIN7870164

The Mouse Monoclonal anti-UPK1A antibody is suitable to detect UPK1A in samples from Human. It has been validated for ELISA and IHC (p).

Quick Overview for UPK1A antibody (AA 114-173) (ABIN7870164)

Target: UPK1A (Uroplakin 1a (UPK1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This UPK1A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: UPK1A-2922

Product Details anti-UPK1A Antibody

Binding Specificity: AA 114-173

Purpose: UPK1A Antibody / Uroplakin 1A

Purification: Protein G affinity chromatography

Immunogen: Amino acids 114-173 were used as the immunogen for the UPK1A antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the UPK1A antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the UPK1A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for UPK1A

Target: UPK1A (Uroplakin 1a (UPK1A))

Alternative Name: UPK1A

Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression.

UniProt: O00322