Girdin antibody (AA 1231-1836)

Catalog No. ABIN7870361

This Rabbit Polyclonal antibody specifically detects Girdin in ELISA, WB and FACS. It exhibits reactivity toward Human and Rat.

Quick Overview for Girdin antibody (AA 1231-1836) (ABIN7870361)

Target: Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Girdin antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-Girdin Antibody

Binding Specificity: AA 1231-1836

Purpose: Girdin Antibody / CCDC88A / GIV

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids K1231-D1836) was used as the immunogen for the Girdin antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Girdin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Girdin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for Girdin

Target: Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))

Alternative Name: Girdin

Background: Girdin, also called G alpha-interacting vesicle-associated protein (GIV), is a protein that in humans is encoded by the CCDC88A gene. This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

UniProt: Q3V6T2