FANCA antibody (AA 1272-1439)

Catalog No. ABIN7870404

The Rabbit Polyclonal anti-FANCA antibody is suitable to detect FANCA in samples from Rat and Mouse. It has been validated for WB, ELISA and FACS.

Quick Overview for FANCA antibody (AA 1272-1439) (ABIN7870404)

Target: FANCA (Fanconi Anemia Group A Protein (FANCA))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-FANCA Antibody

Binding Specificity: AA 1272-1439

Purpose: Fanca Antibody / Fanconi anemia group A protein / FAA

Purification: Antigen affinity purified

Immunogen: Recombinant mouse protein (amino acids E1272-F1439) was used as the immunogen for the Fanca antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Fanca antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Fanca antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for FANCA

Target: FANCA (Fanconi Anemia Group A Protein (FANCA))

Alternative Name: Fanca

Background: Fanconi anaemia, complementation group A, also known as FAA, FACA and FANCA, is a protein which in humans is encoded by the FANCA gene. Acts upstream of or within several processes, including gonad development, regulation of CD40 signaling pathway, and regulation of regulatory T cell differentiation. Predicted to be located in nucleoplasm. Predicted to be part of Fanconi anaemia nuclear complex. Is expressed in several structures, including gut, liver, lung, reproductive system, and spleen. Used to study Fanconi anemia complementation group A. Human ortholog(s) of this gene implicated in several diseases, including Fanconi anemia (multiple), acute myeloid leukemia, esophagus squamous cell carcinoma, ovarian disease (multiple), and skin melanoma. Orthologous to human FANCA (FA complementation group A).

UniProt: Q9JL70

Pathways: DNA Damage Repair