PARP2 antibody (AA 13-253)

Catalog No. ABIN7870461

The Rabbit Polyclonal anti-PARP2 antibody is suitable to detect PARP2 in samples from Human and Rat. It has been validated for WB, ELISA, IF and FACS.

Quick Overview for PARP2 antibody (AA 13-253) (ABIN7870461)

Target: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-PARP2 Antibody

Binding Specificity: AA 13-253

Purpose: PARP2 Antibody

Purification: Affinity purified

Immunogen: A human recombinant partial protein (amino acids R13-E253) was used as the immunogen for the PARP2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PARP2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the PARP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PARP2

Target: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Alternative Name: PARP2

Background: Poly [ADP-ribose] polymerase 2 is an enzyme that in humans is encoded by the PARP2 gene. This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.

UniProt: Q9UGN5

Pathways: DNA Damage Repair