UBXN8 antibody (AA 149-270)
Quick Overview for UBXN8 antibody (AA 149-270) (ABIN7870775)
Target
See all UBXN8 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 149-270
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Purpose
- UBXN8 Antibody / UBX domain-containing protein 8
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Purification
- Antigen affinity purified
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Immunogen
- E. coli-derived recombinant human protein (amino acids N149-N270) was used as the immunogen for the UBXN8 antibody.
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Isotype
- IgG
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Application Notes
- Optimal dilution of the UBXN8 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Storage
- 4 °C,-20 °C
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Storage Comment
- After reconstitution, the UBXN8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- UBXN8 (UBX Domain Protein 8 (UBXN8))
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Alternative Name
- UBXN8
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Background
- P97 or VCP (valosin-containing protein) is a versatile ATPase complex, and many cofactors are required for the p97 functional diversity. This gene encodes one of the p97 cofactors. This cofactor is a transmembrane protein and localized in the endoplasmic reticulum (ER) membrane. It tethers p97 to the ER membrane via its UBX domain. The association of this cofactor with p97 facilitates efficient ER-associated degradation of misfolded proteins. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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UniProt
- O00124
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Pathways
- SARS-CoV-2 Protein Interactome
Target
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